Medicaid coverage of Wegovy and Zepbound added fewer prescriptions than it appeared

Medicaid coverage of Wegovy and Zepbound added fewer prescriptions than it appeared

When a state Medicaid programme starts paying for GLP-1 drugs labeled for obesity, the bill for those drugs goes up. A study in JAMA Health Forum suggests the net increase is smaller than that figure implies, because some of the new obesity-labeled prescriptions appear to replace diabetes-labeled versions of the same molecules, which every state … Read more

26 economic studies on weight-loss drugs, and what ‘cost-effective’ leaves out

Typographic title card: review of 26 economic evaluations of weight-loss drugs

A systematic review has pulled together 26 economic evaluations of the approved weight-loss drugs, and the pattern it reports is worth knowing before anyone quotes “cost-effective” at you. Semaglutide came out ahead of liraglutide consistently enough that the authors call liraglutide generally not cost-effective. Tirzepatide bought the most health of any drug reviewed, and frequently … Read more

Route of administration outranked weight loss in an 800-person preference survey

Route of administration outranked weight loss in an 800-person preference survey

Asked to choose between hypothetical weight-loss drugs, 800 American adults ranked how a drug is taken above how much weight it takes off. In a discrete-choice survey published on 17 September, route of administration was the single most important attribute driving choice, ahead of average weight loss, cardiovascular risk reduction and the share of people … Read more

Lilly-authored analysis says Zepbound offsets other healthcare costs after 55

Does Zepbound offset other healthcare costs after 55?

Eli Lilly announced on 26 August 2026 that a real-world analysis of adults over 55 found lower healthcare costs among people who stayed on Zepbound (tirzepatide) than among matched untreated adults, and framed the result against the $195 monthly net price under Medicare’s GLP-1 Bridge programme. The underlying paper is peer-reviewed and published in Diabetes, … Read more