Hannah Lindqvist 
Children at Massachusetts Boys & Girls Clubs that ran a six-week programme called H2GO! ended the year with a lower BMI z score than children at clubs that did not, according to a cluster randomised trial published in JAMA Network Open on 1 October 2026. The difference was small and only just statistically significant, and … Read more
The World Health Organization published its first guidelines on obesity in children and adolescents on 7 October, as two separate documents: one for children up to the age of 9 and one for adolescents aged 10 to 19. Both put structured diet, physical activity and behaviour-change programmes at the centre of care. For children under … Read more
Australian researchers set out to pool the randomised trials of berberine in polyendocrine metabolic ovarian syndrome, or PMOS, the condition previously called polycystic ovary syndrome. Earlier reviews had presented the supplement as a match for metformin. Every eligible trial, four of them covering 452 women, was rated at high risk of compromised integrity, so none … Read more
A review of 34 randomised trials in PLoS Medicine has tested the standard first-line advice for polyendocrine metabolic ovarian syndrome (PMOS) — the condition long called polycystic ovary syndrome, or PCOS, recently renamed by an international consensus. Structured diet, exercise and behavioural programmes improved fasting insulin, and made regular menstrual cycles more likely, compared with … Read more
Ultra-processed foods are associated with higher rates of seven major health outcomes, obesity and overweight among them, according to a dose-response meta-analysis of 51 prospective cohort studies covering 8,819,894 adults, published on 22 September 2026 in Family Medicine and Community Health. People in the highest intake groups had a 23% higher rate of obesity or … Read more
Semaglutide’s highest-dose weight-loss trial put a small group of its participants inside an MRI scanner, and the results speak to the question that trails every GLP-1 drug: what happens to muscle. Among 55 people drawn from the 1,407-person STEP UP trial, fat volume fell sharply over 72 weeks, thigh muscle volume fell by an amount … Read more
Three endocrinology clinics in Madrid scanned 388 adults with obesity four times over six months on GLP-1 drugs and report that skeletal muscle mass fell by 1.46 kg while mean body weight fell 11.3%. Visceral fat area dropped by 40.6 square centimetres. On those numbers the muscle loss is modest next to the fat loss, … Read more
Just under 17% of 10- to 17-year-olds who started a GLP-1 drug were diagnosed with a nutritional deficiency or a related complication within the following year, an analysis of US insurance claims has found. Most of those diagnoses were vitamin D deficiency. Fewer than a quarter of the teenagers saw anyone for nutrition counselling within … Read more