Greenwich Rx, a 503A compounding pharmacy in Tomball, Texas, is recalling ten lots of compounded glutathione injection nationwide because of potentially elevated endotoxin levels. The company says it has received two reports of patients who needed emergency department care after a glutathione product was given intravenously, although the product was not formulated for IV use. … Read more
Orforglipron, Eli Lilly’s once-daily GLP-1 pill, did not raise the risk of heart attack, stroke or cardiovascular death compared with insulin glargine in 2,749 adults with type 2 diabetes and established heart or kidney disease, according to the ACHIEVE-4 trial published in The Lancet on 30 September. It is the first cardiovascular-outcomes trial of a … Read more
On September 29, 2026, the U.S. Attorney’s Office for the Middle District of Florida and the Justice Department’s Criminal Division announced conspiracy and smuggling charges against Swapnadip Roy and Vicky Ramancha, both Indian nationals, with the FDA’s Office of Criminal Investigations assisting. The indictment alleges that between July 2023 and April 2024 they obtained counterfeit … Read more
Adults with obesity and a raised inflammatory marker who were prescribed a GLP-1 receptor agonist had fewer deaths, heart attacks and strokes over the following decade than closely matched adults given an older weight or diabetes drug, according to a study published on 21 September in the American Journal of Cardiology. The gap was driven … Read more
Prescriptions for GLP-1 receptor agonists written to US adults with no documented reason for taking them rose roughly 15-fold between 2021 and 2025, according to an analysis of electronic health records published on 22 September in Obesity. Among 92.4 million adults whose records showed neither type 2 diabetes nor obesity with a qualifying comorbidity, about … Read more
Three physicians at the University of Missouri-Kansas City and Saint Luke’s Mid America Heart Institute have published a review that does something the injectable-peptide market rarely gets: a compound-by-compound account of what is claimed, what mechanism is proposed, and what could go wrong. It covers BPC-157, TB-500, CJC-1295 and ipamorelin, MK-677, melanotan-II, GHK-Cu, retatrutide and … Read more
Three endocrinology clinics in Madrid scanned 388 adults with obesity four times over six months on GLP-1 drugs and report that skeletal muscle mass fell by 1.46 kg while mean body weight fell 11.3%. Visceral fat area dropped by 40.6 square centimetres. On those numbers the muscle loss is modest next to the fat loss, … Read more
If you take a GLP-1 drug and have spinal fusion surgery scheduled, the largest synthesis of the evidence so far found no sign that the drug makes the operation riskier. A systematic review and meta-analysis published on 17 September pooled seven studies covering 28,525 adults who underwent lumbar fusion, and found no statistically significant difference … Read more