1 in 6 teenagers on a GLP-1 drug had a nutritional deficiency recorded within a year

1 in 6 teenagers on a GLP-1 drug had a nutritional deficiency recorded within a year

Just under 17% of 10- to 17-year-olds who started a GLP-1 drug were diagnosed with a nutritional deficiency or a related complication within the following year, an analysis of US insurance claims has found. Most of those diagnoses were vitamin D deficiency. Fewer than a quarter of the teenagers saw anyone for nutrition counselling within … Read more

A third dual GLP-1/GIP drug reached 18% weight loss in a 120-person trial

A third dual GLP-1/GIP drug reached 18% weight loss in a 120-person trial

A dual GLP-1/GIP receptor agonist made by a Chinese biotech produced up to 18.3% weight loss over 24 weeks in a placebo-controlled phase 2 trial, according to results published on 17 September in Diabetes, Obesity and Metabolism. The drug, BGM0504, acts on the same two gut-hormone receptors as tirzepatide. The trial was small, at 120 … Read more

Teens on GLP-1 drugs had fewer recorded suicide-related events in an 18,444-patient study

Teens on GLP-1 drugs had fewer recorded suicide-related events in an 18,444-patient study

Adolescents with obesity who started semaglutide, liraglutide or tirzepatide were less likely to have a recorded suicide-related event over up to three years than matched adolescents managed with lifestyle intervention, according to an electronic health records study published on 14 September in Diabetes, Obesity and Metabolism. It points away from psychiatric harm in the age … Read more

Nine people reacted to compounded wellness vials shipped to their homes

Peptide Review Desk safety report: compounded wellness vials recalled over elevated endotoxin

Nine people reported fever, chills, chest pain or vomiting after receiving compounded injections that a Houston pharmacy has now recalled nationwide. Centric Compounding is pulling six lots of glutathione, Myer’s Cocktail and Tri-Immune Boost, injectables sold to support immunity, fatigue and general wellness, after the glutathione raw ingredient used to make them was found to … Read more

An online fat burner was found to contain fluoxetine and DNP

Peptide Review Desk safety report: fat burner recalled over undeclared fluoxetine and DNP

A weight-loss supplement sold directly to consumers online has been recalled nationwide after FDA laboratory testing found two undeclared drugs inside the same box. The daytime tablets of Lipofit Extreme Fat Burner 2.0 contained fluoxetine, a prescription antidepressant. The nighttime tablets contained 2,4-dinitrophenol, a substance the FDA describes as a pesticide, dye, wood preservative and … Read more

225 self-harm reports across three GLP-1 drugs, and what the comparison can and cannot show

225 self-harm reports across three GLP-1 drugs, and what the comparison can and cannot show

Between January 2021 and December 2025, Europe’s pharmacovigilance database logged 42,941 adverse-event reports naming liraglutide, semaglutide or tirzepatide as a suspect drug in diabetes or weight management. Of those, 225 involved suicide or self-injury: 141 for semaglutide, 47 for tirzepatide, 37 for liraglutide. A new analysis sets the three against each other and finds such … Read more